Endocrine Abstracts

Primary generalized glucocorticoid resistance or Chrousos syndrome is a rare disorder, which affects all tissues expressing the human glucocorticoid receptor. It has been defined by an absence of overt Cushing’s syndrome (CS) signs (no skin weakness, muscle atrophy, or osteoporosis) associated with biological hypercortisolism consisting of high urinary free cortisol (UFC) and an absence of negative feedback loop of cortisol on HPA, defined as 8-AM cortisol level >50 n...

Mesonephric adenocarcinoma (MA) is an uncommon gynecologic tumor that are thought to arise from embryonal remnants of the mesonephric ducts, also known as Wolffian ducts. Mesonephric-like adenocarcinoma (MLA), despite absence of Wolffian origin, have similar morphology and immunophenotype and exhibit molecular aberrations like MA. These tumors are generally negative for estrogen and progesterone receptor.Case Report: An 83-year-old Spanish female was ref...